BOTOX Indications on CosmeticSurgeryForums.com

BOTOX Cosmetic

PACKAGING AND INDICATIONS

Woman receiving BOTOX Cosmetic

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BOTOX Packaging and Reconstitution Method

How to reconstitute BOTOX:

BOTOX comes in a vial containing 100u (units) of freeze-dried product.
The vials are stored in the physician’s office at -5º F until the BOTOX is usually reconstituted with usually either 2 to 4cc of saline.
At 2cc reconstitution the dose is 50 units per cc or 5 units per 0.1cc.
At 4cc the dose is 25 units per cc or 2.5 units per 0.1cc.
The results are reportedly best if used within 4 hours of reconstitution.

Vial of BOTOX Cosmetic - Allergan, Inc.

BOTOX ® Photos courtesy of Allergan Inc.

Vial of BOTOX Cosmetic

BOTOX Approved Indications

Areas where BOTOX is approved for injection:

Temporary removal of facial wrinkles
Severe underarm sweating
Cervical dystonia - a neurological disorder that causes severe neck and shoulder muscle contractions
Blepharospasm - uncontrollable blinking
Strabismus - misaligned eyes or "lazy eye"
Migraine headaches
Chronic headaches (approval pending 2010**)

** Allergan's new BOTOX treatment for chronic daily headache is expected to file with the FDA a new drug application in mid-2009, with approval expected in the first quarter of 2010.

BOTOX Injection Sites and Recommended Dosages

Muscle Groups Involved - and Amount of BOTOX recommended for injection:

FACE AREA

Forehead Lines:

Muscle group involved: Frontalis Muscle.

Amount of BOTOX recommended for injection: 5 to 25 units depending on the severity of the wrinkles. Horizontal lines are injected every 1 1/2 to 2 cm but high enough from the brow to prohibit brow ptosis (or sag).

BOTOX injection sites for forehead lines

Injection Site for Forehead Lines

Glabella/Frown Lines:

Muscle groups involved: Corrugator - Supercilii - Procerus Muscles.

Amount of BOTOX recommended for injection: 20 to 25 units depending on the severity of the wrinkle/fold. Approximately 5 injections is normally given in this area. Anywhere between 2 an 2.5 units per corrugator and 2.5 units into the procerus can be safely injected. The injector should take care not to inject pass the middle of the brow, or above or past the pupil. This could lead to brow ptosis.

BOTOX injection sites for the frown or glabellar lines

Muscles affected by Botox Injections in the Frown Lines or Glabellar Lines

Crow's Feet (Lateral Orbital Lines):

Muscle groups involved: Orbicularis Oculi and Procerus Muscles.

Amount of BOTOX recommended for injection: 5 to 15 units depending on the severity of the wrinkles or lines. The pleats are injected with 2.5 units. The injector should take care to avoid lid ptosis by injecting too close to the eyelids themselves.

BOTOX injection site for Crow's Feet or Peri-Orbital Lines

Injection site for Crow's Feet or "Peri-Orbital Lines"

Brow Lift:

Muscle groups involved: Frontalis and Obicularis Oculi Muscles

These muscles are antagonistic muscle pairs for eyebrow position - when one contracts the other side will relax - changing eyebrow position. BOTOX can be injected above the outer area of the brow to create a lifting effect.

Amount of BOTOX recommended for injection: Check with your physician on the prescribed dosage of BOTOX for your individual needs. Make sure your injector is skilled in this area or the risk of brow ptosis may increase.

BOTOX injection sites for a brow lift effect

Injection Sites for "Brow Lift"

Bunny Lines (Transverse Nasal):

Amount of BOTOX recommended for injection: 5 to 25 units depending on the severity of the wrinkles or lines.

BOTOX injection sites for the Bunny Lines

Injection Sites for "Bunny Lines"

Peri-Oral Lines (Smoker's Lines):

Muscle group involved: Orbicularis Oris Muscle

Amount of BOTOX recommended for injection: 5 units per lines involved.

BOTOX injection site for Smoker Lines

Injection Site for "Smoker Lines"

Marionette Lines:

Muscle groups involved: Depresssor Anguli Oris and/or Trangularis Muscles

Amount of BOTOX recommended for injection: Check with your physician on the prescribed dosage of BOTOX for your individual needs. This area should be injected with caution due to the side effects that can occur.

BOTOX injection site for the marionette lines

Injection Site for Marionette Lines

Mentalis Dysfunction (Chin "Dents"):

Muscle group involved: Mentalis Muscle - Failed Chin Augmentation or a Mentoplasty

Amount of BOTOX recommended for injection: 20 units of BOTOX can be injected into various points in the Mentalis to relax the mentalis muscle and prevent visible contour irregularities.

BOTOX injection site for Chin Dents

Injection Site for Chin "Dents"

NECK AREA

Vertical Platysma Bands:

Muscle group involved: Platysma Muscle

Amount of BOTOX recommended for injection: Check with your physician on the prescribed dosage of BOTOX for your individual needs.

BOTOX injection site for vertical platysma bands on the neck

Injection Site for Vertical Platysma Bands

UNDERARM AREA - EXCESSIVE SWEATING

Hyperhydrosis or Hyperhidrosis (excessive sweating):

BOTOX can be used to control (excessive sweating) also known as, hyperhydrosis. BOTOX blocks the release of Acetycholine which is the body’s chemical which stimulates the sweat glands.

BOTOX injections have proven to be very useful in diminishing excessive sweating (hyperhidrosis). Hyperhidrosis is a common and extremely distressing condition with a prevalence of 2.8% of the population. For those affected, the condition is debilitating with serious impairment in activities of daily living, social interaction, and occupational activities.

It is divided into primary or idiopathic hyperhidrosis which is usually focal and limited to axilla, palms, soles and face, and secondary hyperhidrosis which can be local or generalized affecting the entire body. Secondary hyperhidrosis is due to a variety of causes including underlying medical conditions, drugs, or exaggerated physiological responses to heat, humidity, or exercise.

BOTOX injection sites for Underarm Sweating

Injection Site for Underarm Sweating

Primary hyperhidrosis is defined as focal visible excessive sweating or at least 6 months duration without apparent cause and associated with at least two of the following characteristics:

Bilateral and relatively symmetrical
Impairs daily activities
Frequency of at least one episode per week
Age of onset less then 25 years
Positive family history
Cessation of focal sweating during sleep

Areas that can be injected for Hyperhydrosis/Hyperhidrosis:

Armpits:
Muscle group involved: Axillary
Palms:
Muscle group involved: Palmaris
Soles of the Feet:
Muscle group involved: Plantaris

BOTOX Syringes

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Other Indications for BOTOX

BOTOX is of course known for it's ability with reducing wrinkles. However, BOTOX and its related chemicals do so much more! BOTOX works by interfering with the transmission of a signal from the nerve end to organ that the nerve controls, such as a muscle or sweat gland and also other tissue. This interference lasts for a limited time and then the signal between the nerve and tissue retuns to normal.

BOTOX is the most popular wrinkle reducing non-invasive treatment that is offered today! But, BOTOX and its potential benefits in the treatment for a number of a medical conditions.

See how BOTOX works

BOTOX Studies with Pain Management:

PAIN TREATMENT - One of the most notable abilities of BOTOX is that it can block the transmission of pain signals.

There are current studies being investigated using BOTOX in the possible treatments:

Chronic Headaches (approval is supposed to be later this year - 2010)
Shingles
Pain associated with the lower back strain
Osteoarthritis

Other Ongoing Studies where BOTOX is being used:

Prostrate Enlargement
Overactive Bladder
Anal Fissures
TMJ (Temporo Mandibular Joint Sydrome - "teeth grinding")
Gastroparesis (condition of Diabetes which interferes with the process of emptying the stomach)

BOTOX Competition Links

More BOTOX Links:

BOTOX FAQ'S
BOTOX Information
BOTOX Side Effects
BOTOX Before and After Photos
Anatomy of the Face and Neck Muscles