Collagen is no longer manufactured by Allergan. Collagen was the "gold standard" of facial wrinkle injections and
augmentation for several decades. Since Collagen is now consider obsolete, the
new "gold standard" is the hyaluronic acid fillers.
Elevess is made
by Anika Therapeutics and was sold by Artes Medical whch was approved for use by
the FDA on April 12, 2007. However, Artes Medical filed for bankruptcy in
December 2008, and Anika Therapeutics needed a new distributor - Coapt Systems. The product name Elevess sounded a lot like the new collagen filler Evolence (which is made by Johnson
and Johnson) so Anika Therapeutics was forced to change Elevess to the new name
Hydrelle / Elevess is categorized as a Cosmetic Tissue Augmentation
Product and is approved for injection into the mid-to-deep dermis for the
correction of moderate-to-severe facial wrinkles and folds such as
folds. Hydrelle’s formulation
contains 0.3% lidocaine for greater patient comfort.
Elevess has the highest concentration of hyaluronic acid of any injectable
filler on the market at 28 mg/ml.Hydrelle has the highest available
concentration of hyaluronic acid and a unique hyaluronic acid cross-linker in
the formulation so that is has stronger durability.
Hydrelle has 28mg/ml of
hyaluronic acid. Cross-linked hyaluronic-based fillers can remain in the face
for up to a year, providing much longer-lasting results than collagen-based
fillers. The product comes packaged in a syringe – l cc with a very thin 30
gauge needle to minimize discomfort.
Hydrelle is the first FDA approved hyaluronic acid based dermal filler to include
an anesthetic (lidocaine) in its formulation. By having the lidocaine already in
the filler this allows for more patient comfort during and after the injection
procedure. Hyaluronic acid has the ability to absorb large quantities of water,
and form complexes with collagen and elastin.
Just like all the other hyaluronic based fillers,
Hydrelle is re-absorbed into
the body over 6 months to a year. If injected in the areas of the face that has
minimal movement, the filler will last longer.